Fifth Disease, also known as erythema infectiosum, is a common viral infection caused by the Parvovirus B19.
Parvovirus B19 spreads through respiratory droplets and can also be transmitted through blood and other bodily fluids.
In children, the telltale sign of fifth disease is a bright-red rash on the cheeks that sometimes shows up six to 11 days after other symptoms. (They can look like they’ve been slapped.)
Fifth disease is one of the most common childhood diseases. About half of all adults (including pregnant women) are already immune to fifth disease because they got sick with the virus in the past.